Novel regulation of inflammasomes by cytokine signalling pathways in gastric disease [ 2013 - 2015 ]

Research Grant

Researchers: Prof Brendan Jenkins (Principal investigator) ,  A/Pr Richard Ferrero ,  Prof Eicke Latz

Brief description Stomach inflammation (gastritis) is strongly associated with Helicobacter pylori bacterial infection, and can also progress to gastric cancer. However, it remains largely unknown how Helicobacter triggers these gastric diseases in people. Using a mouse model which develops gastric inflammation and tumours, our aim is to determine the role of protein complexes in the stomach called inflammasomes in triggering chronic inflammatory responses to Helicobacter that lead to gastric disease.

Funding Amount $AUD 674,772.55

Funding Scheme Project Grants

Notes Standard Project Grant