A novel protease and growth factor regulated signalling system in ovarian cancer [ 2017 - 2019 ]

Research Grant

Researchers: Prof John Hooper (Principal investigator)

Brief description Ovarian cancer is the leading cause of gynaecologic cancer death. Our project focuses on the role in ovarian cancer of a cellular receptor called CDCP1. We have previously shown that CDCP1 promotes growth and spread of ovarian tumours. Recently we have generated new data indicating that CDCP1’s activity is markedly increased by other proteins called proteases and growth factors. In this project we will define how these new pathways function, and if their blockade impedes ovarian cancer.

Funding Amount $AUD 877,262.13

Funding Scheme Project Grants

Notes Standard Project Grant