A novel patch-fluorimetry technique for investigating structural changes during gating of mechanosensitive ion channnels [ 2010 - 2012 ]

Also known as: Illuminating the sturcture and function of ion channels

Research Grant

[Cite as]

Researchers: Prof Boris Martinac (Principal investigator) ,  A/Pr Ben Corry Dr Prithwish Pal

Brief description Membrane proteins, especially membrane channels play an important role in regulating the flow of substances across the cell. Dysfunction in these channels can lead to a variety of diseases. Thus approximately 60% of drug development is targeted against such proteins. In our research, we are looking at membrane channels found in bacteria. Understanding the function of these channels will help us develop novel anti-bacterial agents. It will also aid to understand a role of ion channels in disease.

Funding Amount $AUD 387,018.18

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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