grant

A novel oncogenic alliance in breast cancer [ 2017 - 2019 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1129794]

Researchers: Prof Roger Daly (Principal investigator) ,  Dr Lisa Ooms Prof Sandra Otoole

Brief description Triple negative breast cancer (TNBC) is an aggressive disease subtype that lacks targeted therapies. We have identified a protein associated with TNBC termed SgK269 that regulates the transmission of signals instructing the cell to grow and migrate. SgK269 associates with a closely-related protein termed SgK223 to form a signalling complex. The aim of this project is to characterise the role of this signalling complex in TNBC and determine whether it represents a potential therapeutic target.

Funding Amount $AUD 742,052.64

Funding Scheme Project Grants

Notes Standard Project Grant

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