A novel molecular target capable of abrogating neuroblastoma development [ 2015 - 2017 ]

Research Grant

Researchers: Prof Murray Norris (Principal investigator) ,  Prof Giovanni Perini

Brief description Although modern chemotherapy has significantly improved survival rates for many childhood cancers, the outlook remains dismal for children with advanced staged neuroblastoma. These patients frequently have alterations in the cancer-causing gene called MYCN. Using pre-clinical models of MYCN-driven neuroblastoma and genome sequencing we have discovered a gene that can completely block the action of MYCN and prevent neuroblastoma growth. This work will characterize the function of this novel gene.

Funding Amount $AUD 777,098.00

Funding Scheme Project Grants

Notes Standard Project Grant