A novel genetic element controlling adult hemoglobin production [ 2012 - 2014 ]

Research Grant

Researchers: Prof Stephen Jane (Principal investigator) ,  Prof Peter Fraser

Brief description Disorders of the blood protein hemoglobin are the commonest genetic diseases worldwide, and include thalassemia and sickle cell disease. In this proposal we study two novel mouse lines that exhibit thalassemia, but lack any of the known genetic mutations that cause this disease. These mice afford us the opportunity to make unique observations into how hemoglobin is produced, and thereby provide a platform for new therapeutic approaches in these devastating diseases of the blood.

Funding Amount $AUD 493,907.50

Funding Scheme Project Grants

Notes Standard Project Grant