grant

Novel fluorescent probes of cellular microenvironments to study the mechanism of action of endoperoxide antimalarials [ 2009 - 2014 ]

Also known as: Visualising the means by which the antimalarial drug, artemisinin, kills malaria parasites

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/541904]

Researchers: Prof Leann Tilley (Principal investigator) ,  Dr Nectarios Klonis

Brief description Malaria is responsible for the deaths of about two million children each year. As current drugs become increasingly useless due to the development of parasite resistance, there is an urgent need for new antimalarials. Artemisinin, an ancient Chinese drug that is extracted from wormwood, is now a front-line antimalarial, however its mechanism of action is not clear. Information about how artemisinin works is needed to help design cheap synthetic drugs that work in the same way.

Funding Amount $AUD 983,305.89

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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