grant

Novel feedback inhibition of AMPK by mTORC1 controls cell proliferation under stress [ 2019 - ]

Also known as: 5189222

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/GNT1161262]

Brief description Cancer is a disease of uncontrolled cell growth and division. The AMP-activated protein kinase (AMPK) is the cell’s main energy sensor. AMPK provides protection against cancer, in part through its inhibition of mitosis and cell division. AMPK and TOR signalling is altered in most tumours and better understanding of nutritional control of these signalling pathways offers great potential for better selective therapeutic strategies.

Funding Amount $625,788.00

Funding Scheme Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857