grant

Novel bacterial cysteine proteases targeting innate immunity [ 2016 - ]

Also known as: 5015113

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/GNT1100609]

Researchers: Prof Elizabeth Hartland (Principal investigator)

Brief description Host innate defence relies on the activation of several signalling pathways that regulate inflammation and cell death. Several important bacterial pathogens of humans inject virulence “effector” proteins into infected cells that interrupt host cell signalling pathways. We recently discovered a family of new effector proteins that directly degrade host proteins and block cell death. Here we will characterise this and other members of the family to understand their role during infection.

Funding Amount $797,600.00

Funding Scheme Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857