A novel approach to identify the specific antibody characteristics important for protection from malaria in pregnant women [ 2018 - 2021 ]

Research Grant

Researchers: Prof Stephen Rogerson (Principal investigator) ,  Dr Amy Chung

Brief description Antibody protects against malaria, but the specific characteristics of protective antibody are unknown. Pregnant women lack antibody to parasite protein called VAR2CSA, explaining their malaria susceptibility. Using samples from vaccine trials and clinical studies in pregnant women, and a ‘Systems Serology’ approach, we will determine which naturally-acquired or vaccine induced antibodies protect pregnant women from malaria, and how variation in VAR2CSA sequences affects this protection.

Funding Amount $AUD 1,025,379.93

Funding Scheme Project Grants

Notes Standard Project Grant