Novel Apolipoprotein A-I Mimetic Peptides: a Research Tool and a Therapeutic Agent to Study and Treat Atherosclerosis [ 2011 - 2012 ]

Research Grant

Researchers: Prof Dmitri Sviridov (Principal investigator) ,  Dr Alan Remaley ,  Dr James Shaw ,  Dr Scott Turner

Brief description Drugs affecting lipid metabolism have revolutionized the treatment of heart diseases. There is, however, an urgent need for further reduction of high remaining risk. A most promising direction is increasing levels of _good cholesterol�. A new type of such therapy are simple compounds mimicking structure of good cholesterol. We have synthesized new such compounds that are even more active than good cholesterol. Now we will test these compounds in animals and in clinical trial.

Funding Amount $AUD 266,387.71

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant