grant

Non-mutational phenotypic evolution in metastatic melanoma: the role of the epidermal growth factor receptor and epithelial-mesenchymal transition-like processes in treatment resistance. [ 2013 - 2016 ]

Also known as: Characterisation of the role of mesenchymal phenotypes and EGFR in treatment-resistant melanoma.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1055456]

Researchers: Dr Miles Andrews (Principal investigator)

Brief description Phenotypic change has been identified in multiple settings relating to melanoma progression and metastasis. We have identified a degree of overlap between features of phenotypic plasticity, epithelial-to-mesenchymal transition, and the emergence of treatment resistance. This project will further examine mechanisms underlying these changes, focusing on the role of the epidermal growth factor.

Funding Amount $AUD 140,949.58

Funding Scheme Postgraduate Scholarships

Notes Medical/Dental Postgraduate Scholarship

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Identifiers
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ACN 633 798 857