NOD1 sensing of H. pylori peptidoglycan promotes cell survival and bacterial persistence [ 2015 - 2017 ]

Research Grant

Researchers: A/Pr Richard Ferrero (Principal investigator) ,  Dr Ivo Boneca

Brief description The bacterium H. pylori lives in the stomach of half the world’s population and is a major cause of human disease, including peptic ulcers and stomach cancer. This project will investigate how H. pylori is able to manipulate the host immune system by modifying the composition of its outside layer (the cell wall). In so doing, H. pylori causes changes in cells of the stomach lining that allow the bacterium to persist, but that also may predispose the host to cancer.

Funding Amount $AUD 792,492.69

Funding Scheme Project Grants

Notes Standard Project Grant