Do NK cells limit the long term burden of CMV in older Australians and transplant recipients? [ 2014 - 2017 ]

Research Grant

Researchers: A/Pr Patricia Price (Principal investigator) ,  A/Pr Campbell Witt ,  A/Pr Richard Allcock ,  Dr Silvia Lee ,  Prof Ashley Irish

Brief description Most people are infected with cytomegalovirus at an early age. The virus is not naturally cleared from the body but becomes latent and may be reactivated by stress or inflammation. Repeated immune responses to these reactivations causes more inflammation and wears out the immune system resulting in diseases of aging (eg: cardiovascular disease). Here we investigate which aspects of the immune system can control CMV in healthy people and in renal transplant recipients. We focus on a population of cells called natural killer (NK) cells.

Funding Amount $AUD 413,864.98

Funding Scheme Project Grants

Notes Standard Project Grant