A new paradigm for the control of cellular function: the dynamic reshaping of the epigenome by histone variants [ 2014 - 2017 ]

Research Grant

Researchers: Prof David Tremethick (Principal investigator)

Brief description Our DNA is packaged and partitioned into stable identities, chromosomes, which is critical for proper cell function and the inheritance of our genetic material from one cell generation to the next. Loss of chromosome integrity leads to cancer and therefore the cell must ensure that this does not happen. We have uncovered a new mechanism whereby different components of chromosomes can dynamically move from one location to another to ensure chromosomes remain stable when they are challenged.

Funding Amount $AUD 672,735.18

Funding Scheme Project Grants

Notes Standard Project Grant