New high-risk variants for colorectal cancer: the post-GWAS era [ 2010 - 2013 ]

Research Grant

Researchers: Prof Mark Jenkins (Principal investigator) ,  A/Pr Joanne Young ,  Dr Daniel Buchanan ,  Dr James Dowty ,  Prof John Hopper
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Brief description Our aim is to discover new genes that greatly increase bowel cancer risk. If we can identify these carriers we may be able to prevent them getting cancer. By studying DNA related to bowel cancer, using a novel family design, we will identify families most likely to carry the new genes. We will focus genetic testing, using new techniques, to look for mutations in these prioritised families. Identified mutations will be tested in a 3,500 bowel cancer cases to see how important they are.

Funding Amount $AUD 710,105.60

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant