Towards a new class of reverse transcriptase inhibitor for HIV prevention [ 2014 - 2016 ]

Research Grant

Researchers: Prof Gilda Tachedjian (Principal investigator) ,  A/Pr Nicolas Sluis-Cremer ,  Dr David Chalmers ,  Dr Jamie Simpson ,  Prof Eddy Arnold

Brief description There remains an urgent need for new HIV prevention strategies. New HIV drugs that block the virus by distinct ways are needed to prevent transmission of drug resistant HIV. This study seeks to identify very small molecules called “fragments” that bind to previously undiscovered pockets on the HIV reverse transcriptase to stop its function, and that can be used as building blocks to design more potent HIV drugs to be used solely for HIV prevention.

Funding Amount $AUD 688,833.46

Funding Scheme Project Grants

Notes Standard Project Grant