A new class of inhibitors for the treatment of tuberculosis [ 2015 - 2018 ]

Research Grant

Researchers: A/Pr James Triccas (Principal investigator) ,  A/Pr Peter Rutledge ,  Dr Nicholas West

Brief description Tuberculosis (TB) remains a major cause of mortality and morbidity worldwide, with 1.3 million deaths annually. Some strains of the TB bacterium are resistant to all available drugs. We have identified novel chemical structures that display potent and specific activity against pathogenic mycobacteria. In this proposal we will develop optimised derivatives with more potent activity against mycobacteria, assess their stability and toxicity and determine their mode of action.

Funding Amount $AUD 720,691.68

Funding Scheme Project Grants

Notes Standard Project Grant