grant

A New Class of Anti-Malarial Agents Targetting Apical Membrane Antigen [ 2012 - 2014 ]

Also known as: New Inhibitors that Target a Protein on the Malaria Parasite Surface

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1025150]

Researchers: Prof Raymond Norton (Principal investigator) ,  Dr Sheena Mcgowan Prof Martin Scanlon Prof Peter Scammells

Brief description Malaria is a major global health problem that imposes a substantial burden on the world’s most vulnerable societies. The invasion of host cells by malaria parasites represents an attractive target for therapeutic intervention, and Apical Membrane Antigen 1 (AMA1) plays an essential role in this process. Agents that bind to a key interaction site on AMA1 prevent host cell invasion and thus represent starting points for the development of a new class of anti-malarial drugs.

Funding Amount $AUD 597,598.09

Funding Scheme Project Grants

Notes Standard Project Grant

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