New approaches to improve thrombolysis in ischaemic stroke [ 2013 - 2016 ]

Research Grant

Researchers: Prof Robert Medcalf (Principal investigator) ,  Prof Arnan Mitchell

Brief description Ischaemic stroke is caused by the presence of a blood clot in the brain. The removal of these clots is achieved using an enzyme called tissue-type plasminogen activator (t-PA). While this agent is effective if given to patients within 4.5h of stroke onset, delayed administration can cause cerebral bleeding. This project is to understand how t-PA promotes these unwanted effects in the brain and to devise novel approaches to extend the time window of t-PA administration in these patients.

Funding Amount $AUD 586,076.61

Funding Scheme Project Grants

Notes Standard Project Grant