A New Approach To Restoring Glucose Homeostasis [ 2018 - 2021 ]

Research Grant

Researchers: Prof David Fairlie (Principal investigator) ,  Dr Abishek Iyer

Brief description We have discovered that activating a cell surface protein increases blood sugar levels in mice. This might occur in diabetes and liver disease. We plan to (1) learn which activators of this protein increase glucose; (2) understand how they affect glucose metabolism; (3) study new inhibitors of this protein for blocking increased glucose production; (4) test the potential therapeutic benefits of blocking this protein in mouse models of type 2 diabetes and non-alcoholic fatty liver disease.

Funding Amount $AUD 949,605.32

Funding Scheme Project Grants

Notes Standard Project Grant