Neuropathic pain drugs based on the endogenous opioid peptide Endomorphin 1. [ 2009 - 2010 ]

Research Grant

Researchers: Prof Istvan Toth (Principal investigator) ,  Dr Joanne Blanchfield

Brief description We have developed a new pain drug based on the natural pain killing opioid peptide, Endomorhin 1. The new drug exhibits activity similar to morphine and gabapentin against neuropathic pain in animals but seems to act through a different mechanism. We will complete our preclinical investigation of this compound by assessing its side effect profile and tolerence inducing properties in animals. We will also continue our development of an orally active analogue of this important peptide.

Funding Amount $AUD 209,470.50

Funding Scheme NHMRC Development Grants

Notes Development Grant