grant

Neurogenic diarrhoea: lessons from cholera toxin and related bacterial exotoxins [ 2011 - 2014 ]

Also known as: Effects of cholera toxin on the gut's nervous system

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1006453]

Researchers: Prof Joel Bornstein (Principal investigator) ,  Ms Rachel Gwynne Prof Laura Parry

Brief description Many bacteria that cause diarrhoea act via the gut’s own nervous system to massively increase the transport of water and salt into the lumen of the intestine. In this project we will investigate mechanisms that lead to this over-excitation of the gut’s nervous system to test the idea that this is due to a change in the properties of the final nerve cells in the normal pathway that controls water transport. This will identify novel sites for drug treatments of diarrhoea.

Funding Amount $AUD 543,818.04

Funding Scheme Project Grants

Notes Standard Project Grant

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