A neurogenic basis of obesity hypertension: Role of adipokines and ghrelin in regulating sympathetic vasomotor activity [ 2009 - 2011 ]

Also known as: Altered brain function may cause hypertension in obesity. Which peripheral molecules are important and how do they act?

Research Grant

[Cite as]

Researchers: Prof Geoffrey Head (Principal investigator) ,  A/Pr James Armitage Dr Nina Eikelis Dr Pamela Davern

Brief description During the development of obesity, brain centres are inappropriately activated by factors such as leptin which are released by excess fat accumulation. This reults in high blood pressure. We seek to determine which chemical type of brain neuron is responsible for receiving these signals in a specific brain region in an animal model that closely resembles the human form of the disease. We will focus specifically on areas known to control the sympathetic nervous system.

Funding Amount $AUD 358,035.34

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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