Neurocognitive and social changes associated with unleaded petrol sniffing and abstinence from further sniffing [ 2006 - 2008 ]

Research Grant

Researchers: A/Pr Sheree Cairney (Principal investigator) ,  Prof Alan Clough ,  Prof Bart Currie ,  Prof Paul Maruff ,  Prof Paul Torzillo

Brief description Currently, there is a poor understanding about the nature and permanence of brain damage associated with sniffing petrol. Previously, we used culturally-appropriate assessments of brain function to test Aboriginal petrol sniffers from remote communities in northern Australia. This showed that recreational petrol sniffers who remained living in their communities showed some degree of brain dysfunction that affected their ability to concentrate, remember things, learn, control their emotions and control their behaviour. Petrol sniffing was then completely stopped in these communities. Two years later, among people who had shown brain dysfunction from sniffing petrol, our assessments showed some recovery of some of the brain damage caused by sniffing petrol. Initially, the current study aims to determine the longer-term outcomes for abstinent petrol sniffers by returning to these communities and assessing social and brain function outcomes in the original study participants, now over 10 years since they stopped sniffing petrol. The second part of the study will focus on the specific effects on the brain, behaviour and social function of sniffing unleaded petrol in comparison to leaded petrol, alcohol, other inhalants and polydrug use. It will also further investigate the time course of recovery of brain function and social outcomes in the immediate period following abstinence from petrol sniffing. This will involve recruiting petrol sniffers who move to outstation communities to stop sniffing, and have them perform brain function tests several times over the months or years that they spend recovering. These findings will enable the development of appropriate programs to minimise the harm from petrol sniffing. It will also establish an assessment protocol for the classification of petrol related brain damage that can be used by health professionals such as Aboriginal health workers, nurses and doctors.

Funding Amount $AUD 639,570.61

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant