Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1102977]

Researchers: Dr Sarah Rea (Principal investigator)

Brief description As cells age the "garbage disposal" process within cells slows down, becoming less functional. In inherited forms of dementia the genes involved often code for damaged proteins that "clog up" the disposal system or directly affect the “garbage men”. These defective garbage men genes include SQSTM1/p62, OPTN, VCP and UBQLN2. We will determine how these defective genes lead to build up of garbage in neuronal cells and how leads to disease.

Funding Amount $AUD 583,163.76

Funding Scheme Targeted Calls

Notes NHMRC-ARC Dementia Research Development Fellowship

Identifiers
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