Mutational signatures of DDT: The role of a controversial persistent endocrine disrupting pollutant on prostate cancer aetiology [ 1/1/2021 - 12/31/2023 ]

Research Grant

Brief description No carcinogen or prevention has been identified for prostate cancer (PCa). As carcinogens are commonly mutagens, we will use genomic interrogation to determine if extensive use of the hormone-disrupting pesticide DDT during the 40's to late 80's increased PCa globally. Having access to prostate tumours from men with biochemically confirmed lifelong DDT-exposure, will provide a measurable genomic signature to evaluate the impact of DDT globally, including Australia.

Funding Amount $991,000

Funding Scheme Ideas Grants

Chief Investigator Prof Vanessa Hayes

Notes Ideas Grants