Muscle Vascular Research and Gene Therapy Using Ultrasound [ 2003-01-01 - 2004-12-31 ]

Research Grant

Researchers: A/Prof Mark Febbraio (Chief Investigator) ,  Dr Glenn McConell (Chief Investigator) ,  Dr Stephen Rattigan (Chief Investigator) ,  Dr Stephen Richards (Chief Investigator) ,  Prof Edward Kraegen (Chief Investigator)
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Brief description Muscle Vascular Research and Gene Therapy Using Ultrasound. We seek funds to set up a national facility for ultrasound in muscle vascular research and gene therapy. Ultrasound with microbubbles will be used for the imaging of muscle microvascular blood flow and as a delivery modality for gene constructs to endothelial cells that control blood flow. The technology has application to (i) the assessment and therapeutic treatment of impaired microvascular function as in diabetics; (ii) the assessment of adaptation to physical training and (iii) the development of therapeutic agents used to treat diabetes. We anticipate improved technology that is fully characterized and novel therapeutics that improve microvascular blood flow.

Funding Amount $102,900

Funding Scheme Linkage Infrastructure, Equipment and Facilities

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