grant

Muscle fusion defects may be a common cause of human dystrophies [ 2014 - 2016 ]

Also known as: Muscle fusion and dystrophy

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1065954]

Researchers: Prof Christophe Marcelle (Principal investigator)

Brief description While muscle fusion is a crucial step of muscle formation, it is surprising that human muscle diseases were never associated with muscle fusion defects. We have recently undertaken a genome-wide functional screen using a mouse muscle cell line. We identified 21 genes that were previously associated with muscle dystrophies in human. The aim of this project is to examine the role of those genes during muscle fusion in vivo, using the chick embryo, mouse mutants and lines from patients as models.

Funding Amount $AUD 391,419.12

Funding Scheme Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857