Mucosal vaccine for Hendra virus [ 2012 - 2015 ]

Research Grant

Researchers: Prof Geoffrey Pietersz (Principal investigator)

Brief description Hendra virus (HeV) cause a disease transmitted from bats to horses which in turn infect humans and other horses. There are no drugs or vaccines for HeV. Since humans are infected by inhalation, a vaccine that can generate antibody in the lung and protect from infection will be ideal. We have found that a natural sugar called mannan used with virus proteins and administered via the nostrils to generate such responses. In this project we will prepare this vaccine and use it in a mouse model of HeV infection to see if it can protect the mice.

Funding Amount $AUD 191,582.26

Funding Scheme Targeted Calls

Notes Urgent Research - Hendra Virus