mRNA expression profiling of chronic lymphocytic leukaemia (CLL) cells from in vivo hypoxic microenvironmental niches; applications for in vitro research and clinical management.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1134083]

Brief description Chronic lymphocytic lymphoma (CLL) is the most frequently diagnosed leukaemia in adults and is still considered incurable. CLL cells proliferate in the lymph nodes and bone marrow; these are areas of the human body that are hypoxic when compared to blood. These hypoxic areas affect CLL cell survival, proliferation and treatment resistance. Changes that occur to CLL cells in these areas can be measured by gene expression profiling and modeled in a lab setting to identify targets for treatment.

Funding Amount $AUD 127,629.27

Funding Scheme Postgraduate Scholarships

Notes Medical/Dental Postgraduate Scholarship

Subjects

Identifiers

nhmrc : 1134083
PURL : https://purl.org/au-research/grants/nhmrc/1134083

mRNA expression profiling of chronic lymphocytic leukaemia (CLL) cells from in vivo hypoxic microenvironmental niches; applications for in vitro research and clinical management. [ 2017 - 2019 ]

Research Grant

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