grant

Monocytes/macrophages in chronic liver diseases: cross-talk with hepatocytes and nonparenchymal cells and role in progressive liver injury [ 2011 - 2013 ]

Also known as: Communication between cells of the liver: role in progressive liver injury

Funded by National Health and Medical Research Council
Managed by The University of Queensland
Managed by University of Queensland
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1003108]

Researchers: Prof Elizabeth Powell (Principal investigator) ,  A/Pr Julie Jonsson ,  Prof Andrew Clouston

Brief description More than 170 million people world-wide are chronically infected with the hepatitis C virus. Approximately 10-15% of chronically infected subjects develop cirrhosis with its attendant risks of liver failure and hepatocellular carcinoma. The objective of this important project is to examine the mechanisms by which monocytes and macrophages (cells of the immune system) enhance or impair the progression of liver disease and response to antiviral treatment in patients with chronic hepatitis C.

Funding Amount $AUD 598,645.42

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Clinical Sciences | Gastroenterology and Hepatology | Medical and Health Sciences | chronic inflammation | hepatic fibrosis | hepatic steatosis | hepatitis | insulin resistance | monocyte/macrophage | nonalcoholic steatohepatitis | obesity |
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