Monoclonal antibodies targeting plasma cells as novel therapeutic agents and diagnostic tools [ 2009 - 2009 ]

Research Grant

Researchers: Prof Lynn Corcoran (Principal investigator) ,  Prof David Tarlinton ,  Prof Philip Hodgkin ,  Prof Stephen Nutt

Brief description We have a new tool to identify a very rare immune cell type. This cell makes antibodies, powerful and exquisitely specific proteins that fight infection. In health, antibody-producing cells are beneficial, but in disease (rheumatoid arthritis, lupus and myeloma), these cells cause disease or death. Antibody-producing cells are long-lived. We have no means to specifically deplete them. We are developing reagents to identify and deplete antibody-producing cells to use as novel therapeutic agents.

Funding Amount $AUD 199,275.00

Funding Scheme NHMRC Development Grants

Notes Development Grant