Molecular and structural basis of signalling by TIR domain-containing adaptors in TLR pathways [ 2011 - 2014 ]

Also known as: Understanding the molecular mechanisms of signalling in innate immunity signalling pathways

Research Grant

[Cite as]

Researchers: Prof Bostjan Kobe (Principal investigator) ,  Prof Nick Gay A/Pr Ashley Mansell

Brief description Humans first detect the presence of pathogens and respond to them through specific pathways termed innate immune pathways. The proposed research will study proteins that participate in these pathways, in particular their three-dimensional structures and how they interact with each other, to understand how they work together to mount an immune response, and to find ways to modulate this response in infectious diseases as well as chronic inflammatory diseases.

Funding Amount $AUD 666,417.59

Funding Scheme Project Grants

Notes Standard Project Grant

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