Molecular pathways that control differentiation and function of tissue-resident memory T cells [ 2018 - ]

Research Grant

Researchers: Prof Axel Kallies (Principal investigator) ,  Dr Laura Mackay

Brief description T cells residing in organs such as gut, liver or skin guard against infection and are critical for preventing tumour development. We found that the combined activities of two factors, Blimp1 and Hobit, are critical for the development of these so-called tissue-resident T cells. Using a series of new tools, we will identify how the molecular network required for the development of tissue-resident T cell is established. This may allow us to harness their critical functions in therapy.

Funding Amount $878,340.00

Funding Scheme Project Grants

Notes Standard Project Grant