Molecular memory: how DNA methylation contributes to spatial memory [ 2010 - 2012 ]

Also known as: How the chemistry of DNA contributes to spatial memory

Research Grant

[Cite as]

Researchers: Prof Ryszard Maleszka (Principal investigator) ,  A/Pr Jennifer Cornish Dr Andrew Barron

Brief description The brain stores memories that can last a lifetime and our memory is core to mental health, but we still do not know how memories are stored. Here we explore a radical new theory that memory storage involves chemical modification of the DNA molecule - DNA-methylation. We will examine how memory changes patterns of DNA-methylation, and how modifying DNA-methylation can change memory. Our work will examine the biochemical basis of memory, and will inspire new strategies to treat memory disorders.

Funding Amount $AUD 482,842.67

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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