Molecular mechanisms underlying the positive associations between male gender and leptin with Barretts oesophagus [ 2009 - 2012 ]

Research Grant

Researchers: A/Pr Michelle Hill (Principal investigator)

Brief description Barrett's oesophagus is a disease of the gullet that can lead to the development of oesophageal cancer, which has a very poor outcome. We have shown that the risk of Barrett's oesophagus is greatest in obese males with a high blood level of leptin, a hormone made in fat tissue. The aim of this study is to examine how leptin causes this increased cancer risk, so that new treatments or tests for Barrett's and oesophageal cancer can be developed.

Funding Amount $AUD 387,489.51

Funding Scheme Career Development Fellowships

Notes RD Wright Biomedical CDF