grant

Molecular mechanisms of renal fibrosis [ 2010 - 2012 ]

Also known as: Mechanisms of renal scarring

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/628634]

Researchers: A/Pr Chrishan Samuel (Principal investigator) ,  A/Pr Tim Hewitson

Brief description Fibrosis is a key cause of renal pathology-dysfunction. Relaxin is an endogenous reno-protective factor, and thus has enormous therapeutic potential. However, despite compelling pre-clinical evidence of its efficacy, little is known about relaxin's mechanism of action. These studies will lead to a much better understanding of its signal transduction properties that will allow us to maximise its anti-fibrotic potential; identify new targets for intervention; and design better clinical trials.

Funding Amount $AUD 374,975.32

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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