Molecular genetics of macrophage activation. [ 2003 - 2005 ]

Research Grant

Researchers: Prof David Hume (Principal investigator) ,  Prof Sean Grimmond

Brief description This project concerns the basic biology of white blood cells called macrophages. Macrophages are required for the immediate defence against infection, as well as wound repair and normal turnover of tissues, but they can also produce toxic products that cause illness, especially in inflammatory diseases and cancer. We are attempting to use the availability of mouse genome information to produce a complete picture of the way that macrophages respond to a challenge from a potential disease-causing microorganism, and the influence of genetic differences between individuals.

Funding Amount $AUD 425,250.00

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant