Molecular dissection of cytokine-mediated regulation of human B-cell differentiation. [ 2009 - 2014 ]

Research Grant

Researchers: Dr Lucinda Berglund (Principal investigator)

Brief description Interleukin 21 is a molecule which activates B cells. Defects in this pathway cause immunodeficiency where individuals cannot make antibodies, while constant activation has been reported in mouse models of autoimmunity. Examining these pathways will shed light on the causes of human immune disease, and may reveal molecules that could be targeted for the treatment of immunodeficiency and autoimmunity. Amplification of normal immune responses could lead to the development of improved vaccines.

Funding Amount $AUD 119,314.01

Funding Scheme Postgraduate Scholarships

Notes Dora Lush Biomedical Postgraduate Scholarship