Molecular diagnosis and therapy of autoimmune disease using translational and reverse translational approaches [ 2020-05-20T00:00:00 ]

Research Grant

Brief description We plan to translate our recent discoveries on human gene variants and molecules produced by immune cells (follicular T cells) into effective therapies for autoimmune diseases. This will involve understanding the mechanisms by which the genes and molecules regulate immune tolerance, stratifying patients with autoimmune disease using newly identified biomarkers, trialling existing biologicals according to affected molecular pathway, and taking novel targets through to commercialisation.

Funding Amount $2,331,372

Funding Scheme Investigator Grants

Chief Investigator Prof Carola Vinuesa

Notes Leadership 3