Molecular determinants of drug binding and selectivity at muscarinic acetylcholine receptors [ 2018 - ]

Research Grant

Researchers: Dr David Thal (Principal investigator) ,  A/Pr Paul Gooley ,  Dr Ron Dror

Brief description G protein-coupled receptors (GPCRs) are the largest family of cell surface receptors in the human genome, and drugs targeting these receptors account for 30% of marketed drugs. This project aims to determine high resolution structural information on how drugs bind and specifically interact with GPCRs, which will enable future development of selective and effective drugs.

Funding Amount $816,866.00

Funding Scheme Project Grants

Notes Standard Project Grant