Molecular Characterization of V-ATPase V0 Domain Subunits e1 and e2 in Osteoclast [ 2013 - 2015 ]

Research Grant

Researchers: Prof Minghao Zheng (Principal investigator) ,  A/Pr Nathan Pavlos ,  Dr Tak Sum Cheng

Brief description Osteoporotic fractures in the elderly are often linked to increased mortality rates. Excess bone resorption is a major contributor to the onset of the disease. The proposed project focuses on the investigation of the molecular mechanisms of acid secretion that is required for the bone degradation in body. The project will examine the role of the proton pump in bone resorption and seek potential targets for the treatment of osteoporosis.

Funding Amount $AUD 558,909.92

Funding Scheme Project Grants

Notes Standard Project Grant