Molecular characterization of dengue virus fusion and antiviral inhibitors. [ 2008 - 2010 ]

Research Grant

Researchers: Prof Paul Young (Principal investigator) ,  Prof Alan Mark ,  Prof Bostjan Kobe ,  Prof David Fairlie ,  Prof Karen Lillycrop (Funded by)

Brief description Dengue viruses are transmitted by mosquitoes and cause major epidemics in more than 100 countries around the world, including Australia. Infection with dengue viruses cause severe and sometimes fatal disease. This proposal focuses on the way dengue virus enters cells and the development of drugs that will prevent virus entry. We have already identified compounds that inhibit the entry process of dengue into cells and this project will significantly build on these early findings.

Funding Amount $AUD 573,557.21

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant