grant

The molecular basis of G protein coupled transport [ 2010 - 2012 ]

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/632703]

Researchers: A/Pr Mika Jormakka (Principal investigator) ,  Dr Megan Maher

Brief description G proteins are molecular switches in all organisms, turning fundamental processes on and off . Defects in the functions of these switches can lead to severe diseases, such as cancer. Crucial details regarding the mechanism by which these switches are turned to on are still missing. This proposal will use a bacterial model system, with aims to provide structural and functional detail on the molecular mechanism of the switch in G proteins, and to extend this model to mammalian systems.

Funding Amount $AUD 495,938.66

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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