grant

Molecular basis of Fluoroquinolone resistance [ 2009 - 2011 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/570784]

Researchers: A/Pr Mika Jormakka (Principal investigator)

Brief description Bacterial antibiotic resistance is mediated through specific biological molecules, so-called multidrug transporter proteins, which effectively export drugs from the cell. This proposal aims to solve the 3D structure of a multidrug resistance protein, NorM, which confers resistance to fluoroquinolone type drugs. Through this, we will provide detail into transport across the membrane of cells, and thus present a molecular understanding of bacterial antibiotic resistance.

Funding Amount $AUD 542,521.84

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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