grant

Modulation of Vegfc/Vegfr3 signaling at the extracellular matrix during embryonic lymphangiogenesis [ 2013 - 2015 ]

Also known as: Modulation of Vegfc/Vegfr3 signaling

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1050138]

Researchers: A/Pr Benjamin Hogan (Principal investigator)

Brief description Lymphatic vessels play important roles in vascular diseases and cancer. However, we are yet to understand how they form during development and disease. We recently identified the gene CCBE1, essential for the formation of lymphatic vessels and responsible for lymphatic dysplasia in humans. This study aims to understand the molecular pathway in which CCBE1 acts. This work aims to characterize new molecular pathways in lymphatic vessels in order to identify new therapeutic targets in lymphatic disease and cancer.

Funding Amount $AUD 570,928.77

Funding Scheme Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857