Modulation of neurotherapeutic cell signalling pathways by metallo-complexes as a treatment for Alzheimers disease. [ 2009 - 2012 ]

Research Grant

Researchers: A/Pr Anthony White (Principal investigator) ,  A/Pr Paul Donnelly ,  A/Pr Peter Crouch

Brief description Alzheimer's disease (AD) is an enormous burden on the Australian health care system . We have begun to investigate therapeutic treatments based on triggering protective cell signalling pathways with metal-based compounds. These compounds trigger the activation of a signalling cascade resulting in inhibition of AD-associated symptoms. In this proposal we will further investigate how these compounds modulate specific receptors and cellular kinase activity to protect neurons in the AD brain.

Funding Amount $AUD 653,113.46

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant