grant

Modulation of leishmaniasis by the proinflammatory cytokines TNF [ 2008 - 2012 ]

Also known as: TNF in leishmaniasis

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/485807]

Researchers: Prof Heinrich Korner (Principal investigator)

Brief description We have established a mouse model that has been genetically modified and cannot produce the cytokine tumour necrosis factor. This cytokine is secreted in the beginning of the inflammatory response. If these mice are infected with a parasite they are not able to heal the infection and die quickly. We can demonstrate that these mice cannot regulate the beginning inflammatory response and do not form a cellular infiltrate at the site of infection.

Funding Amount $AUD 288,911.34

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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