grant

Modulation of HIV-1 latency in primary CD4 T cells by chemokines and dendritic cells [ 2008 - 2010 ]

Also known as: Factors controlling latent HIV-1 infection of T cells

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/491154]

Researchers: Prof Sharon Lewin (Principal investigator) ,  A/Pr Anthony Jaworowski A/Pr Paul Cameron

Brief description Although treatment of HIV using antiretroviral drugs has dramatically improved outcome the presence of latent infection in long lived T cells has so far prevented cure of HIV infection. This study examines the roles of chemokines (proteins that control cell migration) and a special type of infection fighting cell, the dendritic cell, in generating latent infection in resting T cells. These studies could potentially identify new ways to treat and potentially cure HIV infection.

Funding Amount $AUD 380,167.94

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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